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KMID : 0353019650020010031
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Korean Journal of Public Health
1965 Volume.2 No. 1 p.31 ~ p.41
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Experimental Studies on Changes of Blood Gas under the Hyperbaric Oxygenation
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Abstract
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This study was attempted to observe changes of blood gas under the condition of different pressure level of hyperbaric oxygenation. Author constructed small size of experimental hyperbaric chamber for this purpose.
Main findings obtained are as follow.
1) On the occasion of acute carbon-monoxide poisoning, hemoglobin in blood increased, while carbon-dioxide and oxygen contents in blood decreased. In a comatose state, carboxyhemoglobin (HbCO)saturation was over 94%.
2) Carbon-dioxide and oxygen contents in blood markedly increased on the occasion of recovery under 100%O₂ I atmospheric pressure while carboxy-hemoglobin saturation % still remained at the dangerous level of blood concentration (66%).
3) By the increase of pressure level of hyperbaric oxygenation, blood gas findings showed to return to normal control value.
4) There was a difference in blood gas findings between the dead & comatose animal by acute CO poisoning.
5) Rabbits showed almost twice of tolerance of rats to CO poisoning.
6) Rabbits showed more rapid dissociation of carboxy-hemoglobin than the rat under same condition.
7) The above results showed that 100%O₂3 atmospheric pressure was necessary one short period of therapy.
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